HILO WAVE is a biostimulator that places a complex of high- and low-molecular-weight hyaluronic acid (Dual-HA) just beneath the skin to relieve deep dryness, restore natural volume and stimulate collagen. Numbing cream is used, and you can return to your routine immediately.
Because this collagen stimulator can be dissolved if a nodule develops, both doctor and patient can feel more comfortable starting treatment.
Dr. Jinhyung Lee Dong-An Joongsim ClinicManufacturer-recommended interval: 3 months
Numbing cream
Occasional redness or swelling
Manufacturer recommendation
Hydration and firmness
Renewed from within
with a biostimulator
HILO WAVE is a biostimulator that combines high- and low-molecular-weight HA in a single complex, DHC® (Dual-HA), injected at a precise depth. It encourages new collagen and elastin throughout the dermis, giving a natural improvement in lift and volume that begins promptly and lasts.
The immediate change comes from HA's hydration and support for the skin barrier; longer-term improvement comes from collagen remodeling. The high-purity, nonanimal HA, sourced from France, is chosen to minimize foreign-body reactions, nodules and immune responses.
Relieves the tight feeling of dryness by replenishing moisture within the skin. High- and low-molecular-weight HA hold water and immediately strengthen the skin barrier.
Skin becomes firmer and fine lines soften over time. The Dual-HA complex stimulates fibroblasts to produce collagen and elastin.
Skin becomes smoother and develops a clearer glow. Restoring moisture and barrier function together helps even out a rough surface.
Restores natural dimension to the front of the cheeks, cheekbones and nasolabial folds. Small amounts placed at several midface points spread above and below the injection layer, filling out hollows across a wider area.
Facial contours feel naturally lifted, and the effect lasts as new collagen and elastin support the skin from within.
Thin, less supported skin gains density and strength. Immediate hydration is followed by collagen remodeling, gradually rebuilding the skin's structure.
Results depend on how treatment is planned and performed. We take time with every patient. A doctor handles your consultation and performs your treatment personally.
Dr. Chang-Hwan Cho was named a Top Ranker for achieving the highest treatment volume in the shortest time, and our clinic received a 2026 HILO WAVE USER TOP5 AWARD. Dr. Soyoun Koo taught Dual-HA collagen booster strategies at ASLS 2026.
Your doctor selects between a cannula technique with minimal downtime and a five-point method using a 34G, 2 mm needle to place 0.2 cc at each point, taking your pain sensitivity and schedule into account.
Nodules most often form when product concentrates in one place. We distribute small amounts evenly across multiple points from the start.
Comfortable treatment without overdoing it
I'd definitely recommend coming here for HILO WAVE 👍 The doctor was so kind and attentive, and the coordinator and staff were lovely. They kept it comfortable and didn't overdo anything. I wish I'd had it sooner. I'm so, so happy with it 👍 I'd seen a lot of advertising and wasn't sure what to expect, but it was really good. Highly recommend ❤️
My skin looks hydrated and firmer
Winter had been taking a toll on my skin, and I was really happy after HILO WAVE. After treatment, my skin looked hydrated and firmer, which made me smile whenever I looked in the mirror. Recovery was easy, and it didn't interfere with my everyday life at all.
My nasolabial folds filled out naturally
With HILO WAVE, the volume looks lovely. Just the area around my nasolabial folds filled out naturally, exactly the effect I wanted. Dr. Jinhyung Lee did my treatment.
I'd recommend it for nasolabial folds!
I'd really recommend HILO WAVE if nasolabial folds bother you. Mine disappeared, and the added volume looks lovely. It looks so natural.
The award recognizes clinics demonstrating extensive clinical experience and treatment skill through active use of HILO WAVE. Dr. Soyoun Koo accepted it on behalf of Dong-An Joongsim Clinic.
The timing of results and the options for managing nodules differ.
| Type | Main ingredient | When results appear | If a nodule develops |
|---|---|---|---|
| Conventional skin booster | HA, amino acids and peptides | 1–2 weeks | - |
| Collagen stimulators | PLLA, CaHA, PCL | 1–3 months | Difficult to dissolve |
| HILO WAVE | High- and low-molecular-weight HA | Immediate and longer-term effects | Can be dissolved with hyaluronidase |
How does HILO WAVE replenish the skin? Two forms of HA provide immediate and longer-term effects. Doctors with extensive experience in this treatment select the injection depth and amount for each face.
The high- and low-molecular-weight HA complex is placed just beneath the skin.
It spreads upward toward the dermis and downward into deeper layers to cover a broad area.
HA improves moisture retention and immediately strengthens the skin barrier.
New collagen and elastin form, gradually firming the skin.
Our approach
For the neck and hands, we use smaller amounts per point than on the face: around 0.05 cc at each of 20 or more closely spaced points, with a cannula used to distribute product broadly.
Interview with Dr. Chang-Hwan Cho, Medical Aesthetic Top Rankers, March 2026
CheeksCheekbonesNasolabial foldsUnder the eyesCheek tissueMouth areaJawlineNeckCompare injectables and thread lifts side by side. The right choice varies from person to person, so your doctor will help you decide at your consultation.
| Treatment | Results | Duration | Comfort | Recovery |
|---|---|---|---|---|
| HILO WAVE | Visible right away | Around 3 months | Mild discomfort | No downtime |
| Re2O | Gradual improvement | Lasts 6 months or more | Mild discomfort | Usually settled by the next day |
| GOURI | Gradual improvement | Lasts 6 months or more | Mild discomfort | No downtime |
| RADIESSE | Visible right away | Lasts 24 months or more | Mild discomfort | No downtime |
| Sculptra | Gradual improvement | Lasts 24 months or more | Mild discomfort | Usually settled by the next day |
HA content per cc
2–3 times that of standard hydrating injections and skin boosters
HILO WAVE official website (HIGHER Corporation) ↗Ultrafine 2 mm needle
Low injection resistance helps even distribution
Medical Aesthetic Top Rankers: interview with Dr. Chang-Hwan Cho, March 2026 (for medical professionals) ↗Recommended full-face amount
Adjusted between 2 and 6 cc according to skin condition
From actors preparing for filming to patients planning a wedding or presentation, many people visit us ahead of an important date. Your doctor plans the timing and combination of treatments around your facial features and schedule.
If your event is tomorrow
This treatment has no downtime and gives an immediate effect, so it can be scheduled the day before an important event. Your doctor adjusts treatment to avoid lingering swelling or redness.
If your event is a month away
We work backward from your event date to plan a course of treatment around HILO WAVE. Our broad range of devices lets us choose a combination that suits your face.
HA's moisturizing effect immediately replenishes the skin.
You can have treatment after work and return to your usual routine the next day.
Patients often return to build on the improvement and bring their skin back to its best condition.
Your doctor handles both your consultation and treatment. A patient coordinator can help with pricing.
Your doctor examines the area you want to treat and discusses the changes you hope to see.
Your doctor assesses the skin and chooses a cannula or needle technique.
Numbing cream helps ease discomfort from the injections.
Small amounts are distributed evenly at multiple points in the planned layer.
After soothing care, you can go home and return to your usual routine.
Our approach
HILO WAVE can be used before laser or device treatments to improve the skin's baseline condition. This sequence aims to reduce the risk of post-treatment pigmentation and reactive redness.
Interview with Dr. Chang-Hwan Cho, Medical Aesthetic Top Rankers, March 2026
Conference lectures and seminars with doctors from around the world.
A device treatment lifts the tissue while HILO WAVE supports the skin's structure. The combination aims to extend benefits that might otherwise fade sooner.
Explore ONDA Lifting →Adding HILO WAVE after SOPRANO TITANIUM lifting supports both facial volume and the skin's underlying structure.
Explore Titanium Lift →The two products complement each other. Including the less painful HILO WAVE can make the overall treatment easier to tolerate.
Explore Re2O →A layered approach: JUVÉLOOK Volume supports deeper tissue, with HILO WAVE above it to improve skin quality.
Explore JUVÉLOOK →Our doctors explain skin concerns relevant to hydration and collagen treatments in clear, practical terms.
ONDA uses microwave energy to improve firmness and contour, while HILO WAVE delivers high- and low-molecular-weight hyaluronic acid within the skin.
The doctors at Dong-An Joongsim Clinic
Daily sunscreen and consistent moisturizing are the foundations of healthier-looking skin.
The doctors at Dong-An Joongsim Clinic
Depending on their ingredients, skin boosters add hydration, support the skin's structure or stimulate collagen production.
The doctors at Dong-An Joongsim ClinicResults depend on how treatment is planned and performed. Check whether a doctor handles consultation and treatment, whether genuine products and equipment are used, and whether treatments can be combined to suit your face. Dong-An Joongsim Clinic has received a HILO WAVE USER TOP5 AWARD. We take time with every patient, with a doctor leading your consultation and performing treatment personally.
Results develop in two stages. HA provides immediate hydration, while collagen remodeling gradually improves firmness. Small amounts can be distributed around hollow-looking nasolabial folds for a natural change. Under-eye treatment requires particular caution: the manufacturer recommends avoiding the eye area, including between the brows, because vascular injection can cause serious complications such as blindness. Your doctor assesses skin thickness and vessel positions, selects the amount and areas, and avoids sites close to the eyes.
The manufacturer recommends a 3-month interval, and many patients return around that time. They often come back to build on the improvement and keep their skin at its best, not because it has fully returned to how it was before.
Numbing cream is usually enough. Discomfort tends to be much lower than with Rejuran or Re2O, and many reviews describe treatment as not painful.
Mild redness and swelling occasionally occur but usually settle quickly. Nodules are very rare but possible. Because HILO WAVE is HA-based, a nodule can be dissolved with hyaluronidase, making it easier to manage than with some collagen stimulators. Following the manufacturer's warning about vascular injection and serious complications including blindness, we avoid thin-skinned areas around the eyes, including between the brows.
HILO WAVE works differently from a filler, which adds volume at a single site. Small amounts of the high- and low-molecular-weight HA complex are spread across multiple points to hydrate and stimulate collagen, giving the midface natural-looking volume. If you have had filler in the same area, leave at least 1 month between treatments, as the manufacturer recommends.
The price depends on whether the whole face or selected areas are treated, the amount used, the cannula or needle technique, and any accompanying treatments. Your doctor assesses the skin and recommends the amount before discussing cost.
Common themes in our patient reviews include natural-looking improvement in hollow nasolabial folds, little pain and easy recovery without disruption to daily life.
Yes. You can return to your usual routine immediately. Avoid rubbing or irritating the treated area for about a week.
| Developer | HIGHERDistributed in Korea by NEOPHARM |
|---|---|
| Type | Class IV medical deviceBiomaterial for tissue repair |
| Ingredients | HA 48 mg / 2.0 mLDHC® high- and low-molecular-weight HA · Nonanimal source, France |
| Recommended interval | 3 months |
| Certifications | MFDS Approved |
We take time with every patient. Your doctor leads the consultation and performs the treatment, with a plan based on your facial features.
