Dr. Chang-Hwan Cho Publishes as First Author in the Journal of Cosmetic Dermatology
A research paper led by Dr. Chang-Hwan Cho of Dong-An Joongsim Clinic has been published in the Journal of Cosmetic Dermatology, an international dermatology journal published by Wiley.
The Journal of Cosmetic Dermatology publishes peer-reviewed clinical and basic research in cosmetic dermatology and is indexed in the Science Citation Index Expanded (SCIE). The clinic’s announcement cites a 2026 Journal Citation Reports impact factor of 3.5 and a Q1 ranking in Dermatology, placing it in the top 25% of the category. Dr. Cho led the paper as both first author and corresponding author.
First authors play a central role in planning and carrying out research and writing the paper; corresponding authors take responsibility for academic communication and the published work. This paper connects GLP-1-based weight-loss treatment, facial aging and the mechanisms of collagen biostimulators from the perspective of a practicing aesthetic physician in Korea.
Paper Title: Mechanotransduction of Collagen Biostimulators: Comparative Signaling and Implications for GLP-1 RA-Associated Facial Aging. Authors: Chang-Hwan Cho · Atsuko Yanagawa · Beomjoon Kim. Comparing the Mechanisms of Collagen Biostimulators: This review compares six collagen biostimulators, including Sculptra (PLLA), JUVÉLOOK (PDLLA), ULTRACOL (PDO), RADIESSE (CaHA) and PCL-based products, through the lens of mechanotransduction. It examines how physical stimuli are converted into cellular signals for collagen production, the differences between materials and the evidence available to date.
A Different Perspective on Facial Aging After GLP-1 Weight Loss: The review considers facial volume loss and skin laxity following GLP-1 treatment in terms of changes in skin tension and fibroblast mechanotransduction, alongside fat loss. It explores the possible role of collagen biostimulators in collagen production and tissue remodeling within this altered environment, while recognizing the need for further clinical research.
Researching the Principles of Skin Regeneration: The JCD publication reflects the clinic’s interest in understanding collagen biostimulators at the cellular and molecular level, including the mechanisms of skin regeneration and collagen production.
